KRR1 Polyclonal Antibody
This is a KRR1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
The SSU is a large ribonucleoprotein consisting of at least 40 proteins and the U3 small nucleolar RNA. It is involved in pre-rRNA processing and ribosome assembly. The SSU is necessary for the biogenesis of the 18S rRNA. Cells that are depleted of SSU proteins will arrest in the G1 phase of the cell cycle. KRR1, also known as HRB2 (HIV-1 Rev binding protein 2) or RIP-1 (Rev interacting protein 1), is a nonribosomal component of the small subunit processome (SSU) . KRR1 is 381 amino acids in length and is evolutionarily conserved among human, yeast, fly, nematode and rice. KRR1 localizes to the nucleolus and is highly expressed in dividing cells. It contains one conserved KH domain (RNA-binding motif) and is a crucial component of the SSU, required for both rRNA maturation and ribosome biogenesis.
Synonyms
HIV 1 Rev binding protein 2, HIV-1 Rev-binding protein 2, HRB2, KRR1, KRR1 small subunit processome component homolog, KRR1, small subunit (SSU) processome component, homolog (yeast), KRR1, Rev interacting protein 1, Rev-interacting protein 1, RIP 1 , Rip-1
Swiss Prot
Q13601
Accession Number
BC016778
Reactivity
Human, Mouse
Immunogen
Fusion protein of human KRR1
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
0.9 mg/mL
Dilution
IHC 1:50-1:300, ELISA 1:5000-1:10000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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