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TIA1 Polyclonal Antibody

This is a TIA1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly (A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature.

Synonyms

Cytotoxic granule associated RNA binding protein 1, Cytotoxic granule associated RNA binding protein, mTIA-1, Nucleolysin TIA 1 isoform p40 , Nucleolysin TIA-1 isoform p40, Nucleolysin TIA1 isoform p40, p40 TIA 1, p40-TIA-1 (containing p15-TIA-1), p40-TIA-1, RNA b

Swiss Prot

P31483

Accession Number

BC015944

Reactivity

Human, Mouse

Immunogen

Full length fusion protein

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB, IHC, ELISA

Purification Method

Antigen affinity purification

Assay Type

Antibody

Concentration

1 mg/mL

Dilution

WB 1:1000-1:5000, IHC 1:40-1:250, ELISA 1:5000-1:10000

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

43 kDa

Observed Molecular Weight

Refer to figures

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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