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GLI1 Polyclonal Antibody

This is a GLI1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

GLI1 (GLI Family Zinc Finger 1) is a Protein Coding gene. Diseases associated with GLI1 include Basal Cell Carcinoma and Necrobiosis Lipoidica. Among its related pathways are Wnt Signaling Pathways: beta-Catenin-independent Wnt/Ca2+ Signaling and Other Non-canonical Wnt Signaling Pathways and G-Beta Gamma Signaling. GO annotations related to this gene include chromatin binding and microtubule binding. An important paralog of this gene is GLI2. This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene.

Synonyms

Gli 1, GLI, GLI family zinc finger 1, GLI Kruppel family member 1, gli1, GLI1, Glioma associated oncogene 1, Glioma associated oncogene homolog 1 (zinc finger protein), Glioma associated oncogene homolog, Glioma-associated oncogene, Oncogene GLI, Zfp 5, Zfp5, Zinc fin

Swiss Prot

P08151

Accession Number

NP005260

Reactivity

Human, Mouse

Immunogen

Synthetic peptide of human GLI1

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB, IHC, ELISA

Purification Method

Antigen affinity purification

Assay Type

Antibody

Concentration

1.08 mg/mL

Dilution

WB 1:500-1:2000, IHC 1:50-1:100, ELISA 1:5000-1:10000

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

118 kDa

Observed Molecular Weight

Refer to figures

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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