F3 Polyclonal Antibody
This is a F3 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants.
Synonyms
CD142, CD142 antigen, Coagulation factor III (thromboplastin tissue factor), Coagulation factor III, F3, FLJ17960, TF, TF, TFA, Thromboplastin, Tissue factor
Swiss Prot
P13726
Accession Number
NP001984
Reactivity
Human
Immunogen
Synthetic peptide of human F3
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
1.1 mg/mL
Dilution
IHC 1:40-1:250, ELISA 1:5000-1:10000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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