RBM15 Polyclonal Antibody
This is a RBM15 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
RNA-binding motif protein 15 (RBM15) belongs to the SPEN protein family, which have repressor function in several signaling pathway, and may bind to RNA through interaction with spliceosome components. It was first described as a 5′ translocation partner of the MAL gene in t (1,22) (p13; q13) infant acute megakaryocytic leukemia, and it functions in murine hematopoiesis through modulating Notch-induced transcriptional activation, which play crucial roles in leukemogenesis. Decreasing RBM15 levels with RNA interference could inhibit the growth and proliferation, block the cell cycle, and induce apoptosis in CML cells.
Synonyms
One twenty two protein, One-twenty two protein 1, OTT, OTT1, Putative RNA-binding protein 15, RBM15, RBM15, RNA binding motif protein 15, RNA-binding motif protein 15
Swiss Prot
Q96T37
Accession Number
BC006397
Reactivity
Human
Immunogen
Fusion protein of human RBM15
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
1.2 mg/mL
Dilution
IHC 1:50-1:300, ELISA 1:5000-1:10000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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