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KCNA10 Polyclonal Antibody

This is a KCNA10 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

KCNA10 (Potassium Voltage-Gated Channel Subfamily A Member 10) is a Protein Coding gene. Among its related pathways are Potassium Channels and Transmission across Chemical Synapses. GO annotations related to this gene include ion channel activity and intracellular cyclic nucleotide activated cation channel activity. An important paralog of this gene is KCNA4.Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog (s) . This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It is specifically regulated by cGMP and postulated to mediate the effects of substances that increase intracellular cGMP. This gene is intronless, and the gene is clustered with genes KCNA2 and KCNA3 on chromosome 1.

Synonyms

Cyclic GMP gated potassium channel, KCA10, Kcn 1, Kcn1, KCNA 10, KCNA10, Kv1.8, Potassium voltage gated channel shaker related subfamily member 10, Potassium voltage gated channel subfamily A member 10, Potassium voltage-gated channel subfamily A member 10, Voltage

Swiss Prot

Q16322

Accession Number

NP005540

Reactivity

Human, Mouse

Immunogen

Synthetic peptide of human KCNA10

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

IHC, ELISA

Purification Method

Antigen affinity purification

Assay Type

Antibody

Concentration

0.66 mg/mL

Dilution

IHC 1:30-1:150, ELISA 1:5000-1:10000

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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