BABAM2 Polyclonal Antibody
This is a BABAM2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Brain and reproductive organ-expressed protein (BRE) is a 415 amino acid protein which binds to the intracellular juxtamembrane domain of the death receptor, tumor necrosis factor receptor 1 (TNF-R1) . BRE also binds to the death receptor, FAS. BRE downregulates TNFa-induced activation of NFkB and may play a role in homeostasis or cellular differentiation in cells of epithelial, neural and germ line origins. It inhibits components of the death-inducing signaling complexes that are necessary for activation of the mitochondria, thereby mediating apoptosis. BRE is strongly expressed in the adrenal cortex, medulla, testis and pancreas, and is weakly expressed in the thymus, thyroid, stomach and small intestine.
Synonyms
6030405P19Rik, AI429776, B830038C02Rik, Brain and reproductive organ expressed (TNFRSF1A modulator), brain and reproductive organ expressed protein, Brain and reproductive organ-expressed protein, BRCA1 A complex subunit BRE, BRCA1-A complex subunit BRE, BRCA1/BR
Swiss Prot
Q9NXR7
Accession Number
BC001251
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein of human BRE
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.5 mg/mL
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
44 kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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