Anti-GUSB Antibody (Center)

Boster Bio Anti-GUSB Antibody (Center) (Catalog # A02234) . Tested in IHC-P, Flow Cytometry, WB application (s) . This antibody reacts with Human, Mouse.

Product Specifications

Background

The GUSB gene encodes beta-glucuronidase (EC 3.2.1.31), a lysosomal hydrolase involved in the stepwise degradation of glucuronic acid-containing glycosaminoglycans (Shipley et al., 1993 [PubMed 7680524]) . It is a tetrameric glycoprotein composed of identical subunits (Oshima et al., 1987 [PubMed 3468507]) . The GUSB gene is mutated in mucopolysaccharidosis type VII (MPS7; MIM 253220) .

Synonyms

Beta-glucuronidase, Beta-G1, GUSB

Gene Name

GUSB

UniProt

P08236

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This GUSB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 335-362 amino acids from the Central region of human GUSB.

Clonality

Polyclonal

Applications

IHC-P, Flow Cytometry, WB

Field of Research

Cell Biology, Metabolism, Microbiology, Signal Transduction, Lysosome

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Plays an important role in the degradation of dermatan and keratan sulfates.

Molecular Weight

74732 Da

Shipping Conditions

Available

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A02234

Product MSDS

https://www.bosterbio.com/msds?sku=A02234

Fragment

Rabbit IgG

Subcellular Location

Lysosome.

Prediction Reactivity

Pig

Available Sizes

Curated Selection

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