Anti-RNF7 Antibody (N-term)

Boster Bio Anti-RNF7 Antibody (N-term) (Catalog # M05620) . Tested in WB, IHC-P application (s) . This antibody reacts with Human, Mouse.

Product Specifications

Background

Probable component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. Through the RING-type zinc finger, seems to recruit the E2 ubiquitination enzyme to the complex and brings it into close proximity to the substrate. Promotes the neddylation of CUL5 via its interaction with UBE2F. May play a role in protecting cells from apoptosis induced by redox agents.

Synonyms

RING-box protein 2, Rbx2, CKII beta-binding protein 1, CKBBP1, RING finger protein 7, Regulator of cullins 2, Sensitive to apoptosis gene protein, RNF7, RBX2, ROC2, SAG

Gene Name

RNF7

UniProt

Q9UBF6

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This RNF7 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 25-57 amino acids from the N-terminal region of human RNF7.

Clonality

Polyclonal

Tissue Specificity

Expressed in heart, liver, skeletal muscle and pancreas. At very low levels expressed in brain, placenta and lung

Applications

WB, IHC-P

Field of Research

Cell Biology, Metabolism

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

10851089

Molecular Weight

12683 Da

Shipping Conditions

Available

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=M05620

Product MSDS

https://www.bosterbio.com/msds?sku=M05620

Fragment

Rabbit IgG

Subcellular Location

Cytoplasm. Nucleus

Available Sizes

Curated Selection

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