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Anti-UBE2C Antibody (C-term)

Boster Bio Anti-UBE2C Antibody (C-term) (Catalog # M01491) . Tested in WB application (s) . This antibody reacts with Human.

Product Specifications

Background

Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys- 11'- and 'Lys-48'-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by initiating 'Lys-11'-linked polyubiquitin chains on APC/C substrates, leading to the degradation of APC/C substrates by the proteasome and promoting mitotic exit.

Synonyms

Ubiquitin-conjugating enzyme E2 C, 6.3.2.19, UbcH10, Ubiquitin carrier protein C, Ubiquitin-protein ligase C, UBE2C, UBCH10

Gene Name

UBE2C

UniProt

O00762

Host

Mouse

Reactivity

Human

Immunogen

This UBE2C antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 137~172 amino acids from the C-terminal region of human UBE2C.

Clonality

Monoclonal

Clone

Clone: 2001CT211.37.61

Applications

WB

Field of Research

Cell Biology

Purification

This antibody is purified through a protein G column, followed by dialysis against PBS.

Dilution

WB: 1:2000

Function

Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by initiating 'Lys-11'-linked polyubiquitin chains on APC/C substrates, leading to the degradation of APC/C substrates by the proteasome and promoting mitotic exit.

Molecular Weight

19652 Da

Shipping Conditions

Available

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=M01491

Product MSDS

https://www.bosterbio.com/msds?sku=M01491

Fragment

IgG1, κ

Prediction Reactivity

Bovine, Monkey, Mouse

Available Sizes

Curated Selection

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