Noggin Mouse Recombinant Protein
Noggin Mouse Recombinant produced in E. coli is a non-glycosylated, disulfide-linked protein consisting of two 206 amino acid polypeptide chains, having a total molecular mass of approximately 46.4 kDa (each chain 23.2 kDa) .
Product Specifications
Synonyms
Noggin; SYM1; SYNS1; NOG
Gene Name
NOG
UniProt
P97466
Reactivity
Mouse
Tissue Specificity
Expressed in condensing cartilage and immature chondrocytes.
Source
Escherichia coli
Sequence
[object Object]
Purification
Greater than 95.0% as determined by SDS-PAGE.
Bioactivity
505
Form
Sterile Filtered White lyophilized (freeze-dried) powder.
Reconstitution
It is recommended to be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in 10mM HAc to a concentration of 0.1-1.0 mg/ml. Further dilutions should be made in appropriate buffered solutions.
Function
Essential for cartilage morphogenesis and joint formation. Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite (PubMed:9585504, PubMed:9603738) . Inhibits chondrocyte differentiation through its interaction with GDF5 and, probably, GDF6 (By similarity) .
Shipping Conditions
Available
Storage Conditions
Lyophilized Mouse Noggin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Mouse Noggin should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) .Please prevent freeze-thaw cycles.
Product Datasheet
https://www.bosterbio.com/datasheet?sku=PROTP97466
Product MSDS
https://www.bosterbio.com/msds?sku=PROTP97466
Other Gene Names
Noggin
Subcellular Location
Secreted.
Available Sizes
Curated Selection
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