BD-3 Beta Defensin-3 Human Recombinant Protein
Beta Defensin-3 Human Recombinant produced in E. coli is a single, non-glycosylated polypeptide chain containing 45 amino acids and having a molecular mass of 5161.2 Dalton. The BD-3 is purified by proprietary chromatographic techniques.
Product Specifications
Synonyms
HBD3; HBP3; DEFB3; HBD-3; HBP-3; DEFB103
Gene Name
DEFB103ADEFB103B
UniProt
P81534
Reactivity
Human
Tissue Specificity
Highly expressed in skin and tonsils, and to a lesser extent in trachea, uterus, kidney, thymus, adenoid, pharynx and tongue. Low expression in salivary gland, bone marrow, colon, stomach, polyp and larynx. No expression in small intestine.
Source
Escherichia coli
Sequence
[object Object]
Purification
Greater than 95.0% as determined by (a) Analysis by RP-HPLC and (b) Analysis by SDS-PAGE.
Form
Sterile Filtered lyophilized (freeze-dried) powder.
Reconstitution
It is recommended to reconstitute the lyophilized Beta Defensin-3 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Function
Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed.
Shipping Conditions
Available
Storage Conditions
Lyophilized Beta Defensin-3 Recombinant although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution BD-3 should be stored at 4°C between 2-7 days and for future use below -18°C.Please prevent freeze-thaw cycles.
Product Datasheet
https://www.bosterbio.com/datasheet?sku=PROTP81534
Product MSDS
https://www.bosterbio.com/msds?sku=PROTP81534
Other Gene Names
Beta-defensin 103
Subcellular Location
Secreted.
Available Sizes
Curated Selection
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