GCP-2 Granulocyte Chemotactic Protein 2 (CXCL6) Human Recombinant Protein
GCP-2 Human Recombinant produced in E. coli is a single, non-glycosylated, polypeptide chain containing 72 amino acids and having a molecular mass of 7.9kDa.
Product Specifications
Synonyms
C-X-C motif chemokine 6; Chemokine alpha 3; CKA-3; Granulocyte chemotactic protein 2; GCP-2; Small-inducible cytokine B6
Gene Name
CXCL6
UniProt
P80162
Reactivity
Human
Source
Escherichia coli
Sequence
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Purification
Greater than 98.0% as determined by (a) Analysis by RP-HPLC and (b) Analysis by SDS-PAGE.
Bioactivity
Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human neutrophils is in a concentration range of 10-50 ng/ml corresponding to a specific activity of 20,000-100,000 IU/mg.
Form
Sterile Filtered White lyophilized (freeze-dried) powder.
Reconstitution
It is recommended to reconstitute the lyophilized GCP-2 in sterile 18M-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Function
Chemotactic for neutrophil granulocytes. Signals through binding and activation of its receptors (CXCR1 and CXCR2) . In addition to its chemotactic and angiogenic properties, it has strong antibacterial activity against Gram-positive and Gram- negative bacteria (90-fold-higher when compared to CXCL5 and CXCL7) .
Shipping Conditions
Available
Storage Conditions
Lyophilized GCP-2 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution GCP-2 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) . Please prevent freeze-thaw cycles.
Product Datasheet
https://www.bosterbio.com/datasheet?sku=PROTP80162
Product MSDS
https://www.bosterbio.com/msds?sku=PROTP80162
Other Gene Names
C-X-C motif chemokine 6
Subcellular Location
Secreted.
Available Sizes
Curated Selection
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