PLGF-1 Placenta Growth Factor-1 Human Recombinant Protein, Sf9
Placenta Growth Factor-1 Human Recombinant produced in insect cells is a homodimer, glycosylated polypeptide chain containing 2 x 131 amino acids and having a total molecular mass of approximately 34 kDa. The PLGF-1 is purified by proprietary chromatographic techniques.
Product Specifications
Synonyms
PIGF; PGF; PLGF-1
Gene Name
PGF
UniProt
P49763
Reactivity
Human
Tissue Specificity
While the three isoforms are present in most placental tissues, PlGF-2 is specific to early (8 week) placenta and only PlGF-1 is found in the colon and mammary carcinomas.
Source
Insect cells
Sequence
[object Object]
Purification
Greater than 95.0% as determined by SDS-PAGE.
Bioactivity
5056
Form
Sterile Filtered White lyophilized (freeze-dried) powder.
Reconstitution
It is recommended to reconstitute the lyophilized Placenta Growth Factor 1 in sterile 0.1M acetic acid not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Function
Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth.
Shipping Conditions
Available
Storage Conditions
Lyophilized Placenta Growth Factor 1 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution PLGF1 should be stored at 4°C between 2-7 days and for future use below -18°C.Please prevent freeze-thaw cycles.
Product Datasheet
https://www.bosterbio.com/datasheet?sku=PROTP49763
Product MSDS
https://www.bosterbio.com/msds?sku=PROTP49763
Other Gene Names
Placenta growth factor
Subcellular Location
Secreted. The three isoforms are secreted but PlGF-2 appears to remain cell attached unless released by heparin.
Available Sizes
Curated Selection
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