Dimethadione

Dimethadione is the primary metabolite of trimethadione. Dimethadione causes depression of neuromuscular transmission. Dimethadione primarily decreases transmitter release from the nerve terminal[1].

Product Specifications

CAS Number

[695-53-4]

UNSPSC

12352005

Hazard Statement

H302+H312+H332, H351

Target

Drug Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/dimethadione.html

Concentration

10mM

Purity

99.93

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(N1)OC(C)(C)C1=O

Molecular Formula

C5H7NO3

Molecular Weight

129.11

Precautions

H302+H312+H332, H351

References & Citations

[1]M T Alderdice, et al. Comparison of the effects of trimethadione and its primary metabolite dimethadione on neuromuscular function and the effects of altered pH on the actions of dimethadione.