PG 34
PG 34 is a weak O-GlcNAc transferase (OGT) inhibitor (IC50=68 μM), and a close structural analog of OSMI-1 (HY-119738) [1].
Product Specifications
CAS Number
[1681056-62-1]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
OGT
Type
Reference compound
Related Pathways
Neuronal Signaling
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/pg-34.html
Purity
98.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(N1)C=CC2=C1C=CC(S(N[C@H](CC3=CC=CC=C3)C(N(CC4=CC=CO4)CC5=CC=CS5)=O)(=O)=O)=C2
Molecular Formula
C28H25N3O5S2
Molecular Weight
547.65
Precautions
H302, H315, H319, H335
References & Citations
[1]Rodrigo F Ortiz-Meoz, et al. A small molecule that inhibits OGT activity in cells. ACS Chem Biol. 2015 Jun 19;10 (6) :1392-7.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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