Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-NKCC1/SLC12A2 Antibody Picoband®

Boster Bio Anti-NKCC1/SLC12A2 Antibody catalog # PA2169. Tested in IF, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Solute carrier family 12 (sodium/potassium/chloride transporters), member 2, also known as NKCC1, is widely distributed throughout the body, especially in organs that secrete fluids, called exocrine glands. By fluorescence in situ hybridization, this gene is mapped to chromosome 5q23.3. The protein encoded by this gene mediates sodium and chloride transport and reabsorption. The encoded protein is a membrane protein and is important in maintaining proper ionic balance and cell volume. This protein is phosphorylated in response to DNA damage. Three transcript variants encoding two different isoforms have been found for this gene.

Synonyms

Solute carrier family 12 member 2; Basolateral Na-K-Cl symporter; Bumetanide-sensitive sodium- (potassium) -chloride cotransporter 1; SLC12A2; NKCC1

Gene Name

Solute carrier family 12 member 2

UniProt

P55011

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human NKCC1, identical to the related mouse and rat sequences.

Clonality

Polyclonal

Tissue Specificity

Expressed in many tissues.

Applications

IF, IHC, WB

Field of Research

Associated Proteins, ATPases, Cancer, Cardiovascular, Hypoxia, Metabolism, Neuroscience, Neurotransmitter, Plasma Membrane, Signal Transduction, Transporters

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Electrically silent transporter system. Mediates sodium and chloride reabsorption. Plays a vital role in the regulation of ionic balance and cell volume.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=PA2169

Product MSDS

https://www.bosterbio.com/msds?sku=PA2169

Fragment

Rabbit IgG

Applications Notes

Western blot, 0.1-0.5μg/ml, Human<br> Immunohistochemistry (Paraffin-embedded Section), 2-5μg/ml, Human, Mouse, Rat, By Heat<br> Immunofluorescence, 5 μg/ml, Human<br>

Other Gene Names

SLC12A2

Subcellular Location

Membrane; Multi-pass membrane protein.

Sequence Similarities

Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.

Protein Name

Solute carrier family 12 member 2

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

FCGR2B Recombinant Protein C-His Tag Lyophilized 20UG
IHUFCGR2BRCHISLY20UG 20 µg

FCGR2B Recombinant Protein C-His Tag Lyophilized 20UG

Ask
View Details
Dynlt1c CRISPR All-in-one AAV vector set (with saCas9)(Mouse)
18768154 3x1.0μg DNA

Dynlt1c CRISPR All-in-one AAV vector set (with saCas9)(Mouse)

Ask
View Details
SPSB3 (NM_080861) Human Tagged ORF Clone Lentiviral Particle
RC206125L3V 200 µL

SPSB3 (NM_080861) Human Tagged ORF Clone Lentiviral Particle

Ask
View Details