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Anti-NRD1/NRDC Antibody Picoband®

Boster Bio Anti-NRD1/NRDC Antibody Picoband® catalog # A05739-1. Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

This gene encodes a zinc-dependent endopeptidase that cleaves peptide substrates at the N-terminus of arginine residues in dibasic moieties and is a member of the peptidase M16 family. This protein interacts with heparin-binding EGF-like growth factor and plays a role in cell migration and proliferation. Multiple transcript variants encoding different isoforms have been found for this gene.

Synonyms

Activator of 90 kDa heat shock protein ATPase homolog 1; AHA1; p38; AHSA1; C14orf3; HSPC322

Gene Name

Activator of HSP90 ATPase activity 1

UniProt

O43847

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human NRD1/NRDC recombinant protein (Position: K427-R967) .

Clonality

Polyclonal

Tissue Specificity

Expressed in numerous tissues, including brain, heart, skeletal muscle and kidney and, at lower levels, liver and placenta.

Applications

WB, Flow Cytometry, ELISA

Field of Research

Chaperones, Golgi Proteins, Protein Trafficking, Signal Transduction

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Acts as a co-chaperone of HSP90AA1. Activates the ATPase activity of HSP90AA1 leading to increase in its chaperone activity. Competes with the inhibitory co-chaperone FNIP1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins (PubMed:27353360) .

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A05739-1

Product MSDS

https://www.bosterbio.com/msds?sku=A05739-1

Fragment

Rabbit IgG

Applications Notes

6

Other Gene Names

NRDC

Subcellular Location

Cytoplasm, cytosol.

Protein Name

N-alpha-acetyltransferase 15, NatA auxiliary subunit

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