Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-PLEKHG5 Antibody Picoband®

Boster Bio Anti-PLEKHG5 Antibody Picoband® catalog # A08522. Tested in ELISA, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Pleckstrin homology domain containing, family G member 5 (PLEKHG5) is a protein that in humans is encoded by the PLEKHG5 gene. This gene encodes a protein that activates the nuclear factor kappa B (NFKB1) signaling pathway. Mutations in this gene are associated with autosomal recessive distal spinal muscular atrophy. Multiple transcript variants encoding different isoforms have been found for this gene.

Synonyms

PHD finger protein 21A; BHC80a; BRAF35-HDAC complex protein BHC80; PHF21A; BHC80; KIAA1696; BM-006

Gene Name

PHD finger protein 21A

UniProt

A0A5F9ZHW8

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human PLEKHG5 recombinant protein (Position: Q58-K974) .

Clonality

Polyclonal

Tissue Specificity

Highly expressed in brain. Expressed at much lower level in other tissues.

Applications

WB, IHC, ICC, IF, ELISA

Field of Research

Cancer, Cell Biology, Cytoskeleton/ECM, ECM Enzymes, Extracellular Matrix, Invasion/Microenvironment, Metalloprotease, Proteolysis/Ubiquitin, Proteolytic Enzymes, Signal Transduction

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. In the BHC complex, it may act as a scaffold. Inhibits KDM1A-mediated demethylation of 'Lys-4' of histone H3 in vitro, suggesting a role in demethylation regulation.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A08522

Product MSDS

https://www.bosterbio.com/msds?sku=A08522

Fragment

Rabbit IgG

Applications Notes

Western blot, 0.25-0.5 μg/ml, Human<br> Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/ml, Human<br> Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human<br> Immunofluorescence, 5 μg/ml, Human<br> ELISA, 0.1-0.5 μg/ml, -<br>

Other Gene Names

PLEKHG5

Subcellular Location

Nucleus.

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

FITC-Linked Polyclonal Antibody to Nucleoporin 50kDa (NUP50)
MBS2051604-01 0.1 mL

FITC-Linked Polyclonal Antibody to Nucleoporin 50kDa (NUP50)

Ask
View Details
FITC-Linked Polyclonal Antibody to Nucleoporin 50kDa (NUP50)
MBS2051604-02 0.2 mL

FITC-Linked Polyclonal Antibody to Nucleoporin 50kDa (NUP50)

Ask
View Details
FITC-Linked Polyclonal Antibody to Nucleoporin 50kDa (NUP50)
MBS2051604-03 0.5 mL

FITC-Linked Polyclonal Antibody to Nucleoporin 50kDa (NUP50)

Ask
View Details
FITC-Linked Polyclonal Antibody to Nucleoporin 50kDa (NUP50)
MBS2051604-04 1 mL

FITC-Linked Polyclonal Antibody to Nucleoporin 50kDa (NUP50)

Ask
View Details
FITC-Linked Polyclonal Antibody to Nucleoporin 50kDa (NUP50)
MBS2051604-05 5 mL

FITC-Linked Polyclonal Antibody to Nucleoporin 50kDa (NUP50)

Ask
View Details
FITC-Linked Polyclonal Antibody to Nucleoporin 50kDa (NUP50)
MBS2051604-06 5x 5 mL

FITC-Linked Polyclonal Antibody to Nucleoporin 50kDa (NUP50)

Ask
View Details