Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-HRD1/SYVN1 Antibody Picoband®

Boster Bio Anti-HRD1/SYVN1 Antibody Picoband® catalog # A02670-3. Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

E3 ubiquitin-protein ligase synoviolin is an enzyme that in humans is encoded by the SYVN1 gene. This gene encodes a protein involved in endoplasmic reticulum (ER) -associated degradation. The encoded protein removes unfolded proteins, accumulated during ER stress, by retrograde transport to the cytosol from the ER. This protein also uses the ubiquitin-proteasome system for additional degradation of unfolded proteins. Sequence analysis identified two transcript variants that encode different isoforms.

Synonyms

Dermatopontin; Tyrosine-rich acidic matrix protein; TRAMP; DPT

Gene Name

Dermatopontin

UniProt

Q86TM6

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human HRD1/SYVN1 recombinant protein (Position: Q68-R604) .

Clonality

Polyclonal

Tissue Specificity

Expressed in fibroblasts, heart, skeletal muscle, brain and pancreas. Expressed at an intermediate level in lung and kidney, and at a low level in liver and placenta. Expressed at a lower level in fibroblasts from hypertrophic scar lesional skin and in fibroblasts from patients with systemic sclerosis than in normal skin fibroblasts.

Applications

WB, ICC, IF, Flow Cytometry, ELISA

Field of Research

Biochemicals, Chemical Type, Signal Transduction

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Seems to mediate adhesion by cell surface integrin binding. May serve as a communication link between the dermal fibroblast cell surface and its extracellular matrix environment. Enhances TGFB1 activity. Inhibits cell proliferation. Accelerates collagen fibril formation, and stabilizes collagen fibrils against low-temperature dissociation (By similarity) .

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A02670-3

Product MSDS

https://www.bosterbio.com/msds?sku=A02670-3

Fragment

Rabbit IgG

Applications Notes

6

Other Gene Names

SYVN1

Subcellular Location

Secreted, extracellular space, extracellular matrix.

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

MES sodium salt
MBS5802790 Inquire

MES sodium salt

Ask
View Details
S100 Calcium Binding Protein A5 (S100A5) Monoclonal Antibody
CAU29400-01 100 µL

S100 Calcium Binding Protein A5 (S100A5) Monoclonal Antibody

Ask
View Details
S100 Calcium Binding Protein A5 (S100A5) Monoclonal Antibody
CAU29400-02 200 µL

S100 Calcium Binding Protein A5 (S100A5) Monoclonal Antibody

Ask
View Details
c-Src (phospho-Y418) polyclonal antibody
BS4675 50ul

c-Src (phospho-Y418) polyclonal antibody

Ask
View Details
BLNK (NM_013314) Human Recombinant Protein
TP762558 50 µg

BLNK (NM_013314) Human Recombinant Protein

Ask
View Details
Human ABHD2 Protein Lysate
MBS136698-01 0.02 mg

Human ABHD2 Protein Lysate

Ask
View Details