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Anti-MARS1 Antibody Picoband®

Boster Bio Anti-MARS1 Antibody Picoband® catalog # A00216-1. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

This gene encodes a member of the class I family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. The encoded protein is a component of the multi-tRNA synthetase complex and catalyzes the ligation of methionine to tRNA molecules.

Synonyms

GTP-binding nuclear protein Ran; Androgen receptor-associated protein 24; GTPase Ran; Ras-like protein TC4; Ras-related nuclear protein; RAN; ARA24; OK/SW-cl.81

Gene Name

GTP-binding nuclear protein Ran

UniProt

P56192

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human MARS1 recombinant protein (Position: R25-E887) .

Clonality

Polyclonal

Tissue Specificity

Expressed in a variety of tissues. .

Applications

WB, Flow Cytometry, ELISA

Field of Research

Small G Proteins, Spindle

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (By similarity) . The complex with BIRC5/ survivin plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules. Acts as a negative regulator of the kinase activity of VRK1 and VRK2. .

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A00216-1

Product MSDS

https://www.bosterbio.com/msds?sku=A00216-1

Fragment

Rabbit IgG

Applications Notes

Western blot, 0.25-0.5 μg/ml/ml, Human<br> Flow Cytometry (Fixed), 1-3 μg/ml/1x10^6 cells, Human<br> ELISA, 0.1-0.5 μg/ml/ml, Human<br>

Other Gene Names

MARS1

Subcellular Location

Nucleus. Cytoplasm. Melanosome. Nucleus envelope . Predominantly nuclear during interphase. Becomes dispersed throughout the cytoplasm during mitosis. Colocalizes with NEMP1 at the nuclear envelope (By similarity) . Identified by mass spectrometry in melanosome fractions from stage I to stage IV. .
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