Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-TRBP/TARBP2 Antibody Picoband®

Boster Bio Anti-TRBP/TARBP2 Antibody Picoband® catalog # A01680-2. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

RISC-loading complex subunit TARBP2 is a protein that in humans is encoded by the TARBP2 gene. HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene binds between the bulge and the loop of the HIV-1 TAR RNA regulatory element and activates HIV-1 gene expression in synergy with the viral Tat protein. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene also has a pseudogene.

Synonyms

Gastrin/cholecystokinin type B receptor; CCK-B receptor; CCK-BR; Cholecystokinin-2 receptor; CCK2-R; CCKBR; CCKRB

Gene Name

Cholecystokinin B receptor

UniProt

Q15633

Host

Rabbit

Reactivity

Human, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human TRBP/TARBP2 recombinant protein (Position: E20-K366) .

Clonality

Polyclonal

Tissue Specificity

Isoform 1 is expressed in brain, pancreas, stomach, the colon cancer cell line LoVo and the T-lymphoblastoma Jurkat, but not in heart, placenta, liver, lung, skeletal muscle, kidney or the stomach cancer cell line AGS. Expressed at high levels in the small cell lung cancer cell line NCI-H510, at lower levels in NCI-H345, NCI-H69 and GLC-28 cell lines, not expressed in GLC-19 cell line. Within the stomach, expressed at high levels in the mucosa of the gastric fundus and at low levels in the antrum and duodenum. Isoform 2 is present in pancreatic cancer cells and colorectal cancer cells, but not in normal pancreas or colonic mucosa. Isoform 3 is expressed in brain, pancreas, stomach, the stomach cancer cell line AGS and the colon cancer cell line LoVo.

Applications

WB, IHC, ICC, IF, Flow Cytometry, ELISA

Field of Research

Endocrine System, Metabolism, More Gpcr, Neuroscience, Neurotransmission, Obesity, Receptors / Channels

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Receptor for gastrin and cholecystokinin. The CKK-B receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, and neuroleptic activity. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A01680-2

Product MSDS

https://www.bosterbio.com/msds?sku=A01680-2

Fragment

Rabbit IgG

Applications Notes

Western blot, 0.25-0.5 μg/ml, Human<br> Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/ml, Human, Rat<br> Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human<br> Flow Cytometry (Fixed), 1-3 μg/1x10^6 cells, Human<br> ELISA, 0.1-0.5 μg/ml, -<br>

Other Gene Names

TARBP2

Subcellular Location

Cell membrane; Multi-pass membrane protein.

Protein Name

Carboxypeptidase M

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

KCNG1 Lentiviral Vector (Mouse) (CMV) (pLenti-GIII-CMV)
25355064 1.0 µg DNA

KCNG1 Lentiviral Vector (Mouse) (CMV) (pLenti-GIII-CMV)

Ask
View Details
Human ALK / ALK Tyrosine Kinase Receptor Recombinant Protein
MBS2902178 Inquire

Human ALK / ALK Tyrosine Kinase Receptor Recombinant Protein

Ask
View Details
Rat MEPE (Matrix Extracellular Phosphoglycoprotein) ELISA Kit
MBS8805825-01 48 Well

Rat MEPE (Matrix Extracellular Phosphoglycoprotein) ELISA Kit

Ask
View Details
Rat MEPE (Matrix Extracellular Phosphoglycoprotein) ELISA Kit
MBS8805825-02 96 Well

Rat MEPE (Matrix Extracellular Phosphoglycoprotein) ELISA Kit

Ask
View Details
Rat MEPE (Matrix Extracellular Phosphoglycoprotein) ELISA Kit
MBS8805825-03 5x 96 Well

Rat MEPE (Matrix Extracellular Phosphoglycoprotein) ELISA Kit

Ask
View Details
Rat MEPE (Matrix Extracellular Phosphoglycoprotein) ELISA Kit
MBS8805825-04 10x 96 Well

Rat MEPE (Matrix Extracellular Phosphoglycoprotein) ELISA Kit

Ask
View Details