Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-Annexin A3 Antibody Picoband® (monoclonal, 2H3H8)

Boster Bio Anti-Annexin A3 Antibody Picoband® (monoclonal, 2H3H8) catalog # M04796-2. Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Annexin A3 is a protein that in humans is encoded by the Annexin A3 gene. The Annexin A3 gene contains 13 exons and spans 58 kb of genomic DNA. The Annexin A3 gene is mapped to 4q21. It is abnormally expressed in fetuses of both IVF and ICSI, which may contribute to the increase risk of birth defects in these ART. This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions in the inhibition of phospholipase A2 and cleavage of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. This protein may also play a role in anti-coagulation.

Synonyms

Cofilin-2; Cofilin, muscle isoform; CFL2

Gene Name

Cofilin 2

UniProt

P12429

Host

Mouse

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

A synthetic peptide corresponding to a sequence in the middle region of human Annexin A3, different from the related mouse sequence by one amino acid, and from the related rat sequence by three amino acids.

Clonality

Monoclonal

Clone

Clone: 2H3H8

Tissue Specificity

Isoform CFL2b is expressed predominantly in skeletal muscle and heart. Isoform CFL2a is expressed in various tissues.

Applications

WB, IHC, Flow Cytometry

Field of Research

Cell Adhesion Proteins, Epigenetics and Nuclear Signaling, Integrins, Mediator Complex, Neuroscience, Receptors, Transcription

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. Its F-actin depolymerization activity is regulated by association with CSPR3. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods. Required for muscle maintenance. May play a role during the exchange of alpha-actin forms during the early postnatal remodeling of the sarcomere.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=M04796-2

Product MSDS

https://www.bosterbio.com/msds?sku=M04796-2

Fragment

Mouse IgG2b

Applications Notes

6

Other Gene Names

ANXA3

Subcellular Location

Cytoskeleton. Nucleus matrix.

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Ugt2b1 Mouse shRNA Plasmid (Locus ID 71773)
TL516647 1 Kit

Ugt2b1 Mouse shRNA Plasmid (Locus ID 71773)

Ask
View Details
JPH4 siRNA (Human)
MBS8237299-01 15 nmol

JPH4 siRNA (Human)

Ask
View Details
JPH4 siRNA (Human)
MBS8237299-02 30 nmol

JPH4 siRNA (Human)

Ask
View Details
JPH4 siRNA (Human)
MBS8237299-03 5x 30 nmol

JPH4 siRNA (Human)

Ask
View Details
FANCD2 Antibody
ABD6800 100 µg

FANCD2 Antibody

Ask
View Details
SCAF1 Protein Vector (Mouse) (pPM-C-HA)
43079024 500 ng

SCAF1 Protein Vector (Mouse) (pPM-C-HA)

Ask
View Details