Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-TRPM2 Antibody Picoband®

Boster Bio Anti-TRPM2 Antibody Picoband® catalog # A01013-1. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Transient receptor potential cation channel subfamily M member 2, also known as TRPM2 is a protein that in humans is encoded by the TRPM2 gene. Using a cosmid/BAC contig, this gene is mapped to chromosome 21q22.3. The protein encoded by this gene is a calcium-permeable cation channel that is regulated by free intracellular ADP-ribose. The encoded protein is activated by oxidative stress and confers susceptibility to cell death. Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.

Synonyms

Complement component C9; Complement component C9a; Complement component C9b; C9

Gene Name

Complement component C9

UniProt

O94759

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human TRPM2 recombinant protein (Position: R398-Y1503) .

Clonality

Polyclonal

Tissue Specificity

Plasma.

Applications

WB, Flow Cytometry, ELISA

Field of Research

Complement, Immunology, Innate Immunity

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C9 is the pore-forming subunit of the MAC.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A01013-1

Product MSDS

https://www.bosterbio.com/msds?sku=A01013-1

Fragment

Rabbit IgG

Applications Notes

6

Other Gene Names

TRPM2

Subcellular Location

Secreted. Cell membrane; Multi-pass membrane protein. Secreted as soluble monomer. Oligomerizes at target membranes, forming a pre-pore. A conformation change then leads to the formation of a 100 Angstrom diameter pore.
Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

PVRL1 (NECTIN1) Mouse Monoclonal Antibody [Clone ID: OTI1B6]
TA503469 100 µL

PVRL1 (NECTIN1) Mouse Monoclonal Antibody [Clone ID: OTI1B6]

Ask
View Details
Cxcl10 (NM_021274) Mouse Tagged Lenti ORF Clone
MR200291L2 10 µg

Cxcl10 (NM_021274) Mouse Tagged Lenti ORF Clone

Ask
View Details
NOC4L Lentiviral Activation Particles (m2)
sc-430328-LAC-2 200 µL

NOC4L Lentiviral Activation Particles (m2)

Ask
View Details