Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-PPFIA1 Antibody Picoband®

Boster Bio Anti-PPFIA1 Antibody Picoband® catalog # A05735-1. Tested in ELISA, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Liprin-alpha-1 is a protein that in humans is encoded by the PPFIA1 gene. The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. This protein binds to the intracellular membrane-distal phosphatase domain of tyrosine phosphatase LAR, and appears to localize LAR to cell focal adhesions. This interaction may regulate the disassembly of focal adhesion and thus help orchestrate cell-matrix interactions. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Synonyms

Activator of 90 kDa heat shock protein ATPase homolog 1; AHA1; p38; AHSA1; C14orf3; HSPC322

Gene Name

Activator of HSP90 ATPase activity 1

UniProt

Q13136

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human PPFIA1 recombinant protein (Position: A198-C1202) .

Clonality

Polyclonal

Tissue Specificity

Expressed in numerous tissues, including brain, heart, skeletal muscle and kidney and, at lower levels, liver and placenta.

Applications

WB, IHC, ICC, IF, ELISA

Field of Research

Chaperones, Golgi Proteins, Protein Trafficking, Signal Transduction

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Acts as a co-chaperone of HSP90AA1. Activates the ATPase activity of HSP90AA1 leading to increase in its chaperone activity. Competes with the inhibitory co-chaperone FNIP1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins (PubMed:27353360) .

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A05735-1

Product MSDS

https://www.bosterbio.com/msds?sku=A05735-1

Fragment

Rabbit IgG

Applications Notes

Western blot, 0.25-0.5 μg/ml, Human<br> Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/ml, Human<br> Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human<br> ELISA, 0.1-0.5 μg/ml, -<br>

Other Gene Names

PPFIA1

Subcellular Location

Cytoplasm, cytosol.

Protein Name

N-alpha-acetyltransferase 15, NatA auxiliary subunit

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

ATM Rabbit pAb (APR22211N)
APR22211N-01 50 µL

ATM Rabbit pAb (APR22211N)

Ask
View Details
ATM Rabbit pAb (APR22211N)
APR22211N-02 100 µL

ATM Rabbit pAb (APR22211N)

Ask
View Details
ATM Rabbit pAb (APR22211N)
APR22211N-03 200 µL

ATM Rabbit pAb (APR22211N)

Ask
View Details
1-(chloroacetyl)-4-(2-oxo-2-pyrrolidin-1-ylethyl)piperazine
sc-345039A 1 g

1-(chloroacetyl)-4-(2-oxo-2-pyrrolidin-1-ylethyl)piperazine

Ask
View Details
CL429 VacciGrade™
vac-c429 5mg

CL429 VacciGrade™

Ask
View Details
PAK5 Polyclonal Antibody
E44H02975 100ul

PAK5 Polyclonal Antibody

Ask
View Details