Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-COL4A2 Antibody

Boster Bio Anti-COL4A2 Antibody Picoband® catalog # A02453-1. Tested in ELISA, IHC applications. This antibody reacts with Human.

Product Specifications

Background

Canstatin, a cleavage product corresponding to the collagen alpha 2 (IV) NC1 domain, possesses both anti-angiogenic and anti-tumor cell activity. It inhibits proliferation and migration of endothelial cells, reduces mitochondrial membrane potential, and induces apoptosis. Specifically induces Fas-dependent apoptosis and activates procaspase-8 and -9 activity. Ligand for alphavbeta3 and alphavbeta5 integrins.

Synonyms

Probable ATP-dependent RNA helicase DDX4; DEAD box protein 4; Vasa homolog; DDX4; VASA

Gene Name

DEAD-box helicase 4

UniProt

P08572

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human COL4A2 recombinant protein (Position: H1666-L1712) .

Clonality

Polyclonal

Tissue Specificity

Expressed only in ovary and testis. Expressed in migratory primordial germ cells in the region of the gonadal ridge in both sexes.

Applications

IHC, ELISA

Field of Research

Signal Transduction, Cell Biology, Cell Cycle, Stem Cells, Cell Differentiation, Cytoskeleton/ECM, Extracellular Matrix, Structures, ECM Proteins, Mesenchymal Stem Cells

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

ATP-dependent RNA helicase required during spermatogenesis (PubMed:10920202, PubMed:21034600) . Required to repress transposable elements and preventing their mobilization, which is essential for the germline integrity (By similarity) . Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons (By similarity) . Involved in the secondary piRNAs metabolic process, the production of piRNAs in fetal male germ cells through a ping-pong amplification cycle (By similarity) . Required for PIWIL2 slicing-triggered piRNA biogenesis: helicase activity enables utilization of one of the slice cleavage fragments generated by PIWIL2 and processing these pre-piRNAs into piRNAs (By similarity) .

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A02453-1

Product MSDS

https://www.bosterbio.com/msds?sku=A02453-1

Fragment

Rabbit IgG

Applications Notes

Immunohistochemistry(Paraffin-embedded Section), 1-2 μg/ml, Human<br> ELISA, 0.1-0.5 μg/ml, -<br>

Other Gene Names

COL4A2

Subcellular Location

Secreted, extracellular space, extracellular matrix.

Protein Name

BAG family molecular chaperone regulator 1

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Mouse Monoclonal RECK Antibody (MM0523-9G19) [Alexa Fluor 647]
NBP2-11863AF647 0.1 mL

Mouse Monoclonal RECK Antibody (MM0523-9G19) [Alexa Fluor 647]

Ask
View Details
Vom1r20 Protein Vector (Rat) (pPM-C-HA)
50006026 500 ng

Vom1r20 Protein Vector (Rat) (pPM-C-HA)

Ask
View Details
Anti-Mouse CD183/CXCR3 Monoclonal Antibody (PE Conjugated) [CXCR3-173]
MBS2558787-01 0.025 mg

Anti-Mouse CD183/CXCR3 Monoclonal Antibody (PE Conjugated) [CXCR3-173]

Ask
View Details
Anti-Mouse CD183/CXCR3 Monoclonal Antibody (PE Conjugated) [CXCR3-173]
MBS2558787-02 0.1 mg

Anti-Mouse CD183/CXCR3 Monoclonal Antibody (PE Conjugated) [CXCR3-173]

Ask
View Details
Anti-Mouse CD183/CXCR3 Monoclonal Antibody (PE Conjugated) [CXCR3-173]
MBS2558787-03 5x 0.1 mg

Anti-Mouse CD183/CXCR3 Monoclonal Antibody (PE Conjugated) [CXCR3-173]

Ask
View Details
Human NFE2L1 ELISA KIT
ELI-23618h 96 Tests

Human NFE2L1 ELISA KIT

Ask
View Details