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Anti-PDE6 beta/PDE6B Antibody Picoband® (monoclonal, 8I2D7)

Boster Bio Anti-PDE6 beta/PDE6B Antibody Picoband® (monoclonal, 8I2D7) catalog # M02659-1. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Photon absorption triggers a signaling cascade in rod photoreceptors that activates cGMP phosphodiesterase (PDE), resulting in the rapid hydrolysis of cGMP, closure of cGMP-gated cation channels, and hyperpolarization of the cell. PDE is a peripheral membrane heterotrimeric enzyme made up of alpha, beta, and gamma subunits. This gene encodes the beta subunit. Mutations in this gene result in retinitis pigmentosa and autosomal dominant congenital stationary night blindness. Multiple transcript variants encoding different isoforms have been found for this gene.

Synonyms

Arylsulfatase A; ASA; Cerebroside-sulfatase; Arylsulfatase A component B; Arylsulfatase A component C; ARSA

Gene Name

Arylsulfatase A

UniProt

P35913

Host

Mouse

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human PDE6 beta/PDE6B recombinant protein (Position: K25-Q237) .

Clonality

Monoclonal

Clone

Clone: 8I2D7

Applications

WB, IHC, ICC, IF, Flow Cytometry

Field of Research

Cancer, Cell Biology, Cell Death, Metabolism, Metabolism Processes, Neurodegenerative Disease, Neurology Process, Neuroscience, Organelles, Pathways and Processes, Signal Transduction, Subcellular Markers, Tags & Cell Markers

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Hydrolyzes cerebroside sulfate.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=M02659-1

Product MSDS

https://www.bosterbio.com/msds?sku=M02659-1

Fragment

Mouse IgG2a

Applications Notes

6

Other Gene Names

PDE6B

Subcellular Location

Lysosome.

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