Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-FAF1 Antibody Picoband®

Boster Bio Anti-FAF1 Antibody Picoband® catalog # A03842-1. Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Fas-associated factor-1 (FAF1) is a Fas-binding pro-apoptotic protein that is a component of the death-inducing signaling complex in Fas-mediated apoptosis. FAF1 is involved in negative regulation of NF-kappaB activation. In addition to the previously known function as a component of the Fas death-inducing signaling complex, i.e. NF-kappaB activity suppressor by cytoplasmic retention of NF-kappaB p65 via physical interaction. hFAF1 was expressed abundantly in testis, skeletal muscle, and heart as 2.8 kb mRNA. Polyclonal antibody against hFAF1 detected 74 kD protein, a deduced protein size from the ORF and 40 kD protein in some cell lines.

Synonyms

AF4/FMR2 family member 4; ALL1-fused gene from chromosome 5q31 protein; Protein AF-5q31; Major CDK9 elongation factor-associated protein; AFF4; AF5Q31, MCEF; HSPC092

Gene Name

AF4/FMR2 family member 4

UniProt

Q9UNN5

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human FAF1 recombinant protein (Position: R91-E650) .

Clonality

Polyclonal

Tissue Specificity

Ubiquitously expressed. Strongly expressed in heart, placenta, skeletal muscle, pancreas and to a lower extent in brain. .

Applications

ELISA, Flow Cytometry, IF, ICC, WB

Field of Research

Epigenetics and Nuclear Signaling, Transcription, Cell Biology, Transcription Factors, Cell Cycle

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Key component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. In the SEC complex, AFF4 acts as a central scaffold that recruits other factors through interactions with ELL proteins (ELL, ELL2 or ELL3) and the P-TEFb complex. In case of infection by HIV-1 virus, the SEC complex is recruited by the viral Tat protein to stimulate viral gene expression. .

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A03842-1

Product MSDS

https://www.bosterbio.com/msds?sku=A03842-1

Fragment

Rabbit IgG

Applications Notes

6

Other Gene Names

FAF1

Subcellular Location

Nucleus . Associates to transcriptionally active chromatin but not at snRNA genes. .

Protein Name

AF4/FMR2 family member 4

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

R2 CRISPR Activation Plasmid (h2)
sc-400624-ACT-2 20 µg

R2 CRISPR Activation Plasmid (h2)

Ask
View Details
Mouse Anti-human HLA-DR/PerCP antibody
SLM-30090M-PerCP 100 µg - PerCP

Mouse Anti-human HLA-DR/PerCP antibody

Ask
View Details
Frozen Tissue Sections, Artery: carotid
CS535477 5x 5 µm

Frozen Tissue Sections, Artery: carotid

Ask
View Details
Adam17 (NM_009615) Mouse Tagged ORF Clone Lentiviral Particle
MR210844L4V 200 µL

Adam17 (NM_009615) Mouse Tagged ORF Clone Lentiviral Particle

Ask
View Details
Recombinant Streptococcus pneumoniae UPF0397 protein SPH_0594 (SPH_0594)
MBS7040696-01 0.02 mg

Recombinant Streptococcus pneumoniae UPF0397 protein SPH_0594 (SPH_0594)

Ask
View Details
Recombinant Streptococcus pneumoniae UPF0397 protein SPH_0594 (SPH_0594)
MBS7040696-02 0.1 mg

Recombinant Streptococcus pneumoniae UPF0397 protein SPH_0594 (SPH_0594)

Ask
View Details