Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-VPRBP/DCAF1 Antibody Picoband®

Boster Bio Anti-VPRBP/DCAF1 Antibody Picoband® catalog # A31776. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

VprBP was first identified as a protein that can interact with HIV-1 viral protein R. It is a component of the CUL4A-RBX1-DDB1-VprBP/DCAF1 E3 ubiquitin-protein ligase complex that could interact with HIV-1 virus Vpr protein and HIV-2 virus Vpx protein. VprBP is a 1,507-amino acid protein that contains conserved domains, including YXXY repeats, the Lis homology motif, and WD40 repeats. Through binding to Vpr, VprBP allows Vpr to modulate the catalytic activity of the CUL4-DDB1 complex, which in turn leads to the induction of G2 phase arrest in the virus-infected cells. Recently it has been reported that VprBP is able to regulate the p53-induced transcription and apoptotic pathway.

Synonyms

Protein Bop; BH3-only protein; Retrotransposon Gag-like protein 10; RTL10; BOP, C22orf29

Gene Name

Retrotransposon Gag like 10

UniProt

Q9Y4B6

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human VPRBP/DCAF1 recombinant protein (Position: M1-R195) .

Clonality

Polyclonal

Tissue Specificity

Ubiquitously expressed.

Applications

WB, IHC, ICC, IF, Flow Cytometry, ELISA

Field of Research

Chemokines, Immunology, Innate Immunity

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Could induce apoptosis in a BH3 domain-dependent manner. The interaction network of Bcl-2 family members may play a key role in modulation RTL10/BOP intrinsic apoptotic signaling activity.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A31776

Product MSDS

https://www.bosterbio.com/msds?sku=A31776

Fragment

Rabbit IgG

Applications Notes

6

Other Gene Names

DCAF1

Subcellular Location

Cell membrane; Lipid-anchor, GPI-anchor.

Protein Name

Lymphocyte antigen 6A-2/6E-1

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

IL1R1, CT (Interleukin-1 receptor type 1, IL-1R-1, IL-1RT-1, IL-1RT1, CD121 antigen-like family member A, Interleukin-1 receptor alpha, Interleukin-1 receptor type I, p80, CD_antigen: CD121a) (MaxLight 405)
MBS6481477-01 0.1 mL

IL1R1, CT (Interleukin-1 receptor type 1, IL-1R-1, IL-1RT-1, IL-1RT1, CD121 antigen-like family member A, Interleukin-1 receptor alpha, Interleukin-1 receptor type I, p80, CD_antigen: CD121a) (MaxLight 405)

Ask
View Details
IL1R1, CT (Interleukin-1 receptor type 1, IL-1R-1, IL-1RT-1, IL-1RT1, CD121 antigen-like family member A, Interleukin-1 receptor alpha, Interleukin-1 receptor type I, p80, CD_antigen: CD121a) (MaxLight 405)
MBS6481477-02 5x 0.1 mL

IL1R1, CT (Interleukin-1 receptor type 1, IL-1R-1, IL-1RT-1, IL-1RT1, CD121 antigen-like family member A, Interleukin-1 receptor alpha, Interleukin-1 receptor type I, p80, CD_antigen: CD121a) (MaxLight 405)

Ask
View Details
FITC Anti-Human CD25 Antibody
MBS4514930-01 20 Tests

FITC Anti-Human CD25 Antibody

Ask
View Details
FITC Anti-Human CD25 Antibody
MBS4514930-02 50 Tests

FITC Anti-Human CD25 Antibody

Ask
View Details
FITC Anti-Human CD25 Antibody
MBS4514930-03 100 Tests

FITC Anti-Human CD25 Antibody

Ask
View Details
FITC Anti-Human CD25 Antibody
MBS4514930-04 200 Tests

FITC Anti-Human CD25 Antibody

Ask
View Details