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Anti-Olig1 Antibody Picoband®

Boster Bio Anti-Olig1 Antibody Picoband® catalog # A06108-3. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Oligodendrocyte transcription factor 1 (OLIG1), also known as class B basic helix-loop-helix protein 6 (BHLHB6) is a protein that in humans is encoded by the OLIG1 gene. This gene is mapped to 21q22.11. This gene is a member of the oligodendrocyte lineage gene family which encodes basic helix-loop-helix transcription factors. Studies in mice show that it is coexpressed with Olig2 in neural progenitors, and has a role in the development and maturation of oligodendrocytes. OLIG1 gene promotes formation and maturation of oligodendrocytes, especially within the brain. It cooperates with OLIG2 to establish the pMN domain of the embryonic neural tube.

Synonyms

Cyclin-dependent kinase 16 (EC:2.7.11.22) ; Cell division protein kinase 16; PCTAIRE-motif protein kinase 1; Serine/threonine-protein kinase PCTAIRE-1; CDK16; PCTAIRE1; PCTK1

Gene Name

Cyclin dependent kinase 16

UniProt

Q8TAK6

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human Olig1 recombinant protein (Position: M1-K271) .

Clonality

Polyclonal

Tissue Specificity

Detected in pancreas islets (at protein level) . Detected in brain and pancreas.

Applications

WB, Flow Cytometry, ELISA

Field of Research

Signal Transduction

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500μg/ml.

Function

Protein kinase that plays a role in vesicle-mediated transport processes and exocytosis. Regulates GH1 release by brain neurons. Phosphorylates NSF, and thereby regulates NSF oligomerization. Required for normal spermatogenesis. Regulates neuron differentiation and dendrite development (By similarity) . Plays a role in the regulation of insulin secretion in response to changes in blood glucose levels. Can phosphorylate CCNY at 'Ser-336' (in vitro) .

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A06108-3

Product MSDS

https://www.bosterbio.com/msds?sku=A06108-3

Fragment

Rabbit IgG

Applications Notes

6

Other Gene Names

OLIG1

Subcellular Location

Cell membrane. Peripheral membrane protein. Cytoplasmic side. Cytoplasm. Secretory vesicle. Synaptosome.

Protein Name

Cyclin-dependent kinase 16

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