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Anti-Kir6.1/KCNJ8 Antibody Picoband®

Boster Bio Anti-Kir6.1/KCNJ8 Antibody Picoband® catalog # A04950-1. Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Potassium inwardly-rectifying channel, subfamily J, member 8, also known as KCNJ8, is a human gene encoding the Kir6.1 protein. Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins. Defects in this gene may be a cause of J-wave syndromes and sudden infant death syndrome (SIDS) .

Synonyms

Prolactin regulatory element-binding protein; Mammalian guanine nucleotide exchange factor mSec12; PREB; SEC12

Gene Name

Prolactin regulatory element-binding protein

UniProt

Q15842

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human Kir6.1/KCNJ8 recombinant protein (Position: M1-S424) .

Clonality

Polyclonal

Tissue Specificity

Ubiquitous. .

Applications

WB, IHC, Flow Cytometry, ELISA

Field of Research

Epigenetics and Nuclear Signaling, Transcription

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500μg/ml.

Function

Guanine nucleotide exchange factor that specifically activates the small GTPase SAR1B. Mediates the recruitement of SAR1B and other COPII coat components to endoplasmic reticulum membranes and is therefore required for the formation of COPII transport vesicles from the ER. .

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A04950-1

Product MSDS

https://www.bosterbio.com/msds?sku=A04950-1

Fragment

Rabbit IgG

Applications Notes

6

Other Gene Names

KCNJ8

Subcellular Location

Endoplasmic reticulum membrane ; Single-pass membrane protein . Nucleus . Concentrates at endoplasmic reticulum exit sites. .

Protein Name

Vesicular acetylcholine transporter

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