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Anti-PAR1/Thrombin Receptor/F2r Antibody Picoband®

Boster Bio Anti-PAR1/Thrombin Receptor/F2r Antibody Picoband® catalog # A03352-2. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Proteinase-activated receptor 1  (PAR1), also known as the  coagulation factor II (thrombin) receptor,   is a protein  that in humans is encoded by the  F2R  gene. By fluorescence in situ hybridization, this gene is mapped to 5q13, confirming its presence as a single locus in the human genome. PAR1 is a  G protein-coupled receptor  involved in the regulation of  thrombotic  response. Proteolytic cleavage leads to the activation of the receptor. The expression of PAR1 is both required and sufficient to promote growth and invasion of breast carcinoma cells in a xenograft mouse model.&nbsp

Synonyms

Proteinase-activated receptor 1; PAR-1; Thrombin receptor; F2r; Par1

Gene Name

Coagulation factor II (thrombin) receptor

UniProt

P26824

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived rat PAR1/Thrombin Receptor/F2r recombinant protein (Position: R137-A432) .

Clonality

Polyclonal

Tissue Specificity

Platelets and vascular endothelial cells.

Applications

ELISA, Flow Cytometry, WB

Field of Research

Signal Transduction

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A03352-2

Product MSDS

https://www.bosterbio.com/msds?sku=A03352-2

Fragment

Rabbit IgG

Applications Notes

6

Other Gene Names

F2r

Subcellular Location

Cell membrane. Multi-pass membrane protein.

Protein Name

Proteinase-activated receptor 1

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