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Anti-Carbonic Anhydrase III/CA3 Antibody Picoband®

Boster Bio Anti-Carbonic Anhydrase III/CA3 Antibody Picoband® catalog # PB10049. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Carbonic anhydrase III (CA3) is an enzyme that in humans is encoded by the CA3 gene. CA3 is a member of a multigene family (at least six separate genes are known) that encode carbonic anhydrase isozymes. The gene spans 10.3 kb and contains seven exons and six introns. Using a cDNA clone of the CA3 gene in the study of human-rodent hybrids, the gene was mapped to chromosome 8 which carries a cluster of CA genes. The expression of the CA3 gene is strictly tissue specific and present at high levels in skeletal muscle and much lower levels in cardiac and smooth muscle. A proportion of carriers of Duchenne muscle dystrophy have a higher CA3 level than normal.

Synonyms

Carbonic anhydrase 3;4.2.1.1; Carbonate dehydratase III; Carbonic anhydrase III; CA-III; CA3

Gene Name

Carbonic anhydrase 3

UniProt

P07451

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E. coli-derived human CA3 recombinant protein (Position: D14-E235) . Human CA3 shares 92.3% and 91.4% amino acid (aa) sequence identity with mouse and rat CA3, respectively.

Clonality

Polyclonal

Tissue Specificity

Muscle specific.

Applications

IHC, WB

Field of Research

Associated Proteins, Cardiovascular, Cell Biology, Cell Type Markers, Hypoxia

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Reversible hydration of carbon dioxide.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=PB10049

Product MSDS

https://www.bosterbio.com/msds?sku=PB10049

Fragment

Rabbit IgG

Applications Notes

Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, Mouse, Rat, By Heat <br>Western blot, 0.1-0.5μg/ml, Mouse, Rat, Human<br>

Other Gene Names

CA3

Subcellular Location

Cytoplasm.

Protein Name

Carbonic anhydrase 3

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