Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-APC2 Antibody Picoband®

Boster Bio Anti-APC2 Antibody Picoband® catalog # PB10041. Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

APC2, which is also called APCL, is a deduced 2,303-amino acid protein that contains an N-terminal coiled-coil domain, followed by an armadillo domain and five 20-amino acid repeats. The human APC2 gene is mapped to chromosome 19p13.3. It is found that the 20-amino acid repeat domain of APCL could bind beta-catenin (CTNNB1) and deplete the intracellular beta-catenin pool. A reporter gene assay revealed that APCL could regulate interaction of beta-catenin with T cell-specific transcription factors (TCF7), although less efficiently than APC.

Synonyms

Adenomatous polyposis coli protein 2; Adenomatous polyposis coli protein-like; APC-like; APC2; APCL

Gene Name

Adenomatous polyposis coli protein 2

UniProt

O95996

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human APC2, different from the related mouse sequence by two amino acids.

Clonality

Polyclonal

Tissue Specificity

Widely expressed (at protein level) . Specifically expressed in the CNS. .

Applications

WB

Field of Research

Cell Biology, Cell Cycle, Cell Division, Proteasome / Ubiquitin, Proteolysis/Ubiquitin

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Promotes rapid degradation of CTNNB1 and may function as a tumor suppressor. May function in Wnt signaling. .

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=PB10041

Product MSDS

https://www.bosterbio.com/msds?sku=PB10041

Fragment

Rabbit IgG

Applications Notes

Western blot, 0.1-0.5μg/ml, Human<br>

Other Gene Names

APC2

Subcellular Location

Cytoplasm, cytoskeleton . Golgi apparatus . Cytoplasm . Cytoplasm, perinuclear region . Associated with actin filaments (PubMed:11691822) . Associated with microtubule network (PubMed:10644998, PubMed:11691822) . .

Protein Name

Adenomatous polyposis coli protein 2

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

HOMER2 Adenovirus (Mouse)
23782055 1.0 ml

HOMER2 Adenovirus (Mouse)

Ask
View Details
Interleukin 24 (IL24) Antibody
abx306736-01 20 µg

Interleukin 24 (IL24) Antibody

Ask
View Details
Interleukin 24 (IL24) Antibody
abx306736-02 50 µg

Interleukin 24 (IL24) Antibody

Ask
View Details
Interleukin 24 (IL24) Antibody
abx306736-03 100 µg

Interleukin 24 (IL24) Antibody

Ask
View Details
Interleukin 24 (IL24) Antibody
abx306736-04 200 µg

Interleukin 24 (IL24) Antibody

Ask
View Details
Interleukin 24 (IL24) Antibody
abx306736-05 1 mg

Interleukin 24 (IL24) Antibody

Ask
View Details