Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-RIP140/NRIP1 Antibody Picoband®

Boster Bio Anti-RIP140/NRIP1 Antibody catalog # RP1095. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Nuclear receptor-interacting protein 1 (NRIP1), also known as receptor-interacting protein 140 (RIP140), is a protein that in humans is encoded by the NRIP1 gene. It is a nuclear protein that specifically interacts with the hormone-dependent activation domain AF2 of nuclear receptors. Also known as RIP140, this protein is a key regulator which modulates transcriptional activity of a variety of transcription factors, including the estrogen receptor. RIP140 has an important role in regulating lipid and glucose metabolism, and regulates gene expression in metabolic tissues including heart, skeletal muscle, and liver. A major role for RIP140 in adipose tissue is to block the expression of genes involved in energy dissipation and mitochondrial uncoupling, including uncoupling protein 1 and carnitine palmitoyltransferase 1b.

Synonyms

Nuclear receptor-interacting protein 1; Nuclear factor RIP140; Receptor-interacting protein 140; NRIP1

Gene Name

Nuclear receptor-interacting protein 1

UniProt

P48552

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human RIP140, different from the related mouse sequence by two amino acids.

Clonality

Polyclonal

Applications

WB

Field of Research

2339, Co-Factors, Epigenetics and Nuclear Signaling, Nuclear Hormone Receptors, Nuclear Receptors, Nuclear Signaling, Nuclear Signaling Pathways, Signal Transduction, Signaling Pathway, Transcription

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Modulates transcriptional activation by steroid receptors such as NR3C1, NR3C2 and ESR1. Also modulates transcriptional repression by nuclear hormone receptors. Positive regulator of the circadian clock gene expression: stimulates transcription of ARNTL/BMAL1, CLOCK and CRY1 by acting as a coactivator for RORA and RORC. .

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=RP1095

Product MSDS

https://www.bosterbio.com/msds?sku=RP1095

Fragment

Rabbit IgG

Applications Notes

Western blot, 0.1-0.5μg/ml, Mouse, Rat, Human<br>

Other Gene Names

NRIP1

Subcellular Location

Nucleus . Localized to discrete foci and redistributes to larger nuclear domains upon binding to ligand- bound NR3C1.

Protein Name

Nuclear receptor-interacting protein 1

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

VENTX2 shRNA Plasmid (h)
sc-90826-SH 20 µg

VENTX2 shRNA Plasmid (h)

Ask
View Details
Mouse Tartrate-Resistant Acid Phosphatase 5b ELISA Kit
MBS3807045-01 48 Well

Mouse Tartrate-Resistant Acid Phosphatase 5b ELISA Kit

Ask
View Details
Mouse Tartrate-Resistant Acid Phosphatase 5b ELISA Kit
MBS3807045-02 96 Well

Mouse Tartrate-Resistant Acid Phosphatase 5b ELISA Kit

Ask
View Details
Mouse Tartrate-Resistant Acid Phosphatase 5b ELISA Kit
MBS3807045-03 5x 96 Well

Mouse Tartrate-Resistant Acid Phosphatase 5b ELISA Kit

Ask
View Details
Mouse Tartrate-Resistant Acid Phosphatase 5b ELISA Kit
MBS3807045-04 10x 96 Well

Mouse Tartrate-Resistant Acid Phosphatase 5b ELISA Kit

Ask
View Details
KRT86 Adenovirus (Human)
26056051 1.0 ml

KRT86 Adenovirus (Human)

Ask
View Details