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Anti-Peroxiredoxin 6/PRDX6 Antibody Picoband®

Boster Bio Anti-Peroxiredoxin 6/PRDX6 Antibody Picoband® catalog # PB9350. Tested in IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

PRDX6 is also known as PRX, p29 or AOP2. The protein encoded by this gene is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell; it can reduce H (2) O (2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury.

Synonyms

Peroxiredoxin-6;1.11.1.15;1-Cys peroxiredoxin;1-Cys PRX;24 kDa protein; Acidic calcium-independent phospholipase A2; aiPLA2;3.1.1.-; Antioxidant protein 2; Liver 2D page spot 40; Non-selenium glutathione peroxidase; NSGPx;1.11.1.9; Red blood cells page spot 12; PRDX6; AOP2, KIAA0106

Gene Name

Peroxiredoxin-6

UniProt

P30041

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human Peroxiredoxin 6 recombinant protein (Position: E15-P224) . Human Peroxiredoxin 6 shares 90% and 91% amino acid (aa) sequence identity with mouse and rat Peroxiredoxin 6, respectively.

Clonality

Polyclonal

Tissue Specificity

Synthesized in numerous tissues (including tumors) and secreted into most extracellular body fluids, such as plasma, uterine fluid, saliva, gingival crevicular fluid, tears, seminal fluid, and milk.

Applications

IHC, ICC, WB

Field of Research

Atherosclerosis, Cancer, Cancer Metabolism, Cardiovascular, Cell Biology, Heart Disease, Lipid Metabolism, Metabolism, Mitochondrial Markers, Mitochondrial Metabolism, Oxidative Stress, Pathways and Processes, Redox Metabolism, Signal Transduction, Vascular Inflammation

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Involved in redox regulation of the cell. Can reduce H (2) O (2) and short chain organic, fatty acid, and phospholipid hydroperoxides. May play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=PB9350

Product MSDS

https://www.bosterbio.com/msds?sku=PB9350

Fragment

Rabbit IgG

Applications Notes

Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, Rat, By Heat<br>Western blot, 0.1-0.5μg/ml, Human, Mouse, Rat<br>Immunocytochemistry , 0.5-1μg/ml, Human

Other Gene Names

PRDX6

Subcellular Location

Cytoplasm . Lysosome . Cytoplasmic vesicle . Also found in lung secretory organelles. .

Sequence Similarities

Belongs to the AhpC/TSA family. Rehydrin subfamily.

Protein Name

Peroxiredoxin-6

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