Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-Galectin 3/LGALS3 Antibody Picoband®

Boster Bio Anti-Galectin 3/LGALS3 Antibody Picoband® catalog # PB9279. Tested in IHC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Galectin-3 (GAL3), also known as LGALS3, MAC2 or GALBP, is a member of the lectin family, of which 14 mammalian galectins have been identified. Galectin-3 is encoded by a single gene, it located on chromosome 14, locus q21– q22. It is expressed in the nucleus, cytoplasm, mitochondrion, cell surface, and extracellular space. Studies have also shown that the expression of galectin-3 is implicated in a variety of processes associated with heart failure, including myofibroblast proliferation, fibrogenesis, tissue repair, inflammation, and Ventricular remodeling. Galectin-3 is expressed in various tissues and organs, but is significantly absent in normal hepatocytes.

Synonyms

Galectin-3; Gal-3;35 kDa lectin; Carbohydrate-binding protein 35; CBP 35; Galactose-specific lectin 3; IgE-binding protein; L-34 galactoside-binding lectin; Laminin-binding protein; Lectin L-29; Mac-2 antigen; Lgals3

Gene Name

Galectin-3

UniProt

P16110

Host

Rabbit

Reactivity

Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived mouse Galectin 3 recombinant protein (Position: K153-I264) . Mouse Galectin 3 shares 88% and 91% amino acid (aa) sequence identity with human and rat Galectin 3, respectively.

Clonality

Polyclonal

Tissue Specificity

The highest levels are found in activated macrophages.

Applications

IHC, WB

Field of Research

Cancer, Cell Cycle, Cell Division, Oncoproteins, Tumor Biomarkers

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells (By similarity) . .

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=PB9279

Product MSDS

https://www.bosterbio.com/msds?sku=PB9279

Fragment

Rabbit IgG

Applications Notes

Western blot, 0.1-0.5μg/ml, Mouse, Rat<br> Immunohistochemistry (Paraffin-embedded Section), 2-5μg/ml, Mouse, Rat, By Heat<br>

Other Gene Names

LGALS3

Subcellular Location

Cytoplasm. Nucleus. Secreted. Secreted by a non-classical secretory pathway and associates with the cell surface.

Sequence Similarities

Contains 3 cystatin kininogen-type domains.

Protein Name

Galectin-3

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Mouse Monoclonal CD48/SLAMF2 Antibody (156-4H9) [Allophycocyanin]
NBP1-43403APC 0.1 mL

Mouse Monoclonal CD48/SLAMF2 Antibody (156-4H9) [Allophycocyanin]

Ask
View Details
DIABLO antibody
20R-1288 100 ug

DIABLO antibody

Ask
View Details
Cat Golgin A4 (GOLGA4) ELISA Kit
MBS9912138 Inquire

Cat Golgin A4 (GOLGA4) ELISA Kit

Ask
View Details
Olfr921 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse)
33551114 3 x 1.0 µg

Olfr921 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse)

Ask
View Details
CTNNAL1 (NM_003798) Human Tagged ORF Clone Lentiviral Particle
RC217961L3V 200 µL

CTNNAL1 (NM_003798) Human Tagged ORF Clone Lentiviral Particle

Ask
View Details