MK-0773

MK-0773 is a selective androgen receptor modulators (SARMs) that binds to AR with an IC50 of 6.6 nM.

Product Specifications

CAS Number

[606101-58-0]

Product Name Alternative

PF-05314882

UNSPSC

12352005

Target

Androgen Receptor

Type

Reference compound

Related Pathways

Vitamin D Related/Nuclear Receptor

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/MK-0773.html

Concentration

10mM

Purity

99.92

Solubility

DMSO : 33.33 mg/mL (ultrasonic)

Smiles

O=C([C@H]1CC[C@]2([H])[C@]1(C)CC[C@]3([H])[C@@]4(C)C=C(F)C(N(C)[C@]4([H])CC[C@]32[H])=O)NCC5=NC6=CC=CN=C6N5

Molecular Formula

C27H34FN5O2

Molecular Weight

479.59

References & Citations

[1]Schmidt A, et al. Discovery of the selective androgen receptor modulator MK-0773 using a rational development strategy based on differential transcriptional requirements for androgenic anabolism versus reproductive physiology. J Biol Chem. 2010 May 28;285