Human Soluble Siglec-2 / CD22 ELISA Kit, PRO
Human Soluble Siglec-2 / CD22 ELISA Kit, PRO is expressed from Human
Product Specifications
Background
B-cell receptor CD22 is also known as Sialic acid-binding Ig-like lectin 2 (Siglec-2), B-lymphocyte cell adhesion molecule (BL-CAM), T-cell surface antigen Leu-14, which belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. CD22 mediates B-cell B-cell interactions, and may be involved in the localization of B-cells in lymphoid tissues. Siglec-2 / CD22 binds sialylated glycoproteins, one of which is CD45. Siglec2 / CD22 plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.
Reactivity
Human
Target
Siglec-2
Applications
The kit is developed for quantitative detection of natural and recombinant human Siglec-2/CD22 in serum, plasma and cell culture supernatants.
Stability
Keep the unopened kit stored at 2-8 °C. Avoid using the kit beyond its expiration date. The opened kit should be stored per components table. The shelf life is 30 days from the date of opening.
Format
Solid
Shipping Conditions
RT
Storage Conditions
2-8°C
Package Size
96tests*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/CEA-B046.pdf
Species
Human
CAS Number
7732-18-5
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