Norethindrone

Norethindrone is a female progestin approved by FDA for the treatment of endometriosis, uterine bleeding caused by abnormal hormone levels, and secondary amenorrhea.

Product Specifications

CAS Number

[68-22-4]

Product Name Alternative

Norethisterone

UNSPSC

12352211

Hazard Statement

H302, H351, H360, H410

Target

Bacterial; Progesterone Receptor

Type

Reference compound

Related Pathways

Anti-infection; Vitamin D Related/Nuclear Receptor

Applications

Neuroscience-Neuromodulation

Field of Research

Endocrinology; Cancer

Assay Protocol

https://www.medchemexpress.com/norethindrone.html

Purity

99.37

Solubility

DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 2.7 mg/mL (ultrasonic)

Smiles

C[C@@]1([C@]2(O)C#C)[C@](CC2)([H])[C@@](CCC3=CC4=O)([H])[C@]([C@@]3([H])CC4)([H])CC1

Molecular Formula

C20H26O2

Molecular Weight

298.42

Precautions

H302, H351, H360, H410

References & Citations

[1]Muneyyirci-Delale O, et al. Effect of norethindrone acetate in the treatment of symptomatic endometriosis. Int J Fertil Womens Med. 1998 Jan-Feb;43 (1) :24-7.|[2]Kaser DJ, et al. Use of norethindrone acetate alone for postoperative suppression of endometriosis symptoms. J Pediatr Adolesc Gynecol. 2012 Apr;25 (2) :105-8.|[3]Maier WE, et al. Pharmacology and toxicology of ethinyl estradiol and norethindrone acetate in experimental animals. Regul Toxicol Pharmacol. 2001 Aug;34 (1) :53-61.|[4]Cheng DC, et al. Norethindrone acetate inhibition of triglyceride synthesis and release by rat hepatocytes. Atherosclerosis. 1983 Jan;46 (1) :41-8.