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Anti-MLK1 MAP3K9 Antibody

Boster Bio Anti-MLK1 MAP3K9 Antibody catalog # A07599. Tested in ELISA, IHC applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Mitogen-activated protein kinase kinase kinase 9;2.7.11.25; Mixed lineage kinase 1; MAP3K9; MLK1, PRKE1;

Gene Name

MAP3K9

UniProt

P80192

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human MAP3K9. AA range:561-610

Clonality

Polyclonal

Tissue Specificity

Expressed in epithelial tumor cell lines of colonic, breast and esophageal origin.

Applications

IHC, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Once activated, acts as an upstream activator of the MKK/JNK signal transduction cascade through the phosphorylation of MAP2K4/MKK4 and MAP2K7/MKK7 which in turn activate the JNKs. The MKK/JNK signaling pathway regulates stress response via activator protein-1 (JUN) and GATA4 transcription factors. Plays also a role in mitochondrial death signaling pathway, including the release cytochrome c, leading to apoptosis.

Molecular Weight

121895 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A07599

Product MSDS

https://www.bosterbio.com/msds?sku=A07599

Fragment

IgG

Other Gene Names

Mitogen-activated protein kinase kinase kinase 9

Protein Name

Mitogen-activated protein kinase kinase kinase 9

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