Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-DOCK 180 Antibody

Boster Bio Anti-DOCK 180 Antibody catalog # A03440-1. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Dedicator of cytokinesis protein 1;180 kDa protein downstream of CRK; DOCK180; DOCK1;

Gene Name

DOCK1

UniProt

Q14185

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human DOCK1. AA range:1661-1710

Clonality

Polyclonal

Tissue Specificity

Highly expressed in placenta, lung, kidney, pancreas and ovary. Expressed at intermediate level in thymus, testes and colon.

Applications

WB, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Along with DOCK1, mediates CRK/CRKL regulation of epithelial and endothelial cell spreading and migration on type IV collagen (PubMed:19004829) . Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1 (PubMed:8657152) .

Molecular Weight

215346 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A03440-1

Product MSDS

https://www.bosterbio.com/msds?sku=A03440-1

Fragment

IgG

Other Gene Names

Dedicator of cytokinesis protein 1

Subcellular Location

Cytoplasm . Membrane . Recruited to membranes via its interaction with phosphatidylinositol 3,4,5-trisphosphate. .

Protein Name

Dedicator of cytokinesis protein 1

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Research Grade Vepalimomab
MBS1563863-01 0.1 mg

Research Grade Vepalimomab

Ask
View Details
Research Grade Vepalimomab
MBS1563863-02 1 mg

Research Grade Vepalimomab

Ask
View Details
Research Grade Vepalimomab
MBS1563863-03 5x 1 mg

Research Grade Vepalimomab

Ask
View Details
hsa-miR-4314 miRNA Agomir
MBS8311724-01 5 nmol

hsa-miR-4314 miRNA Agomir

Ask
View Details
hsa-miR-4314 miRNA Agomir
MBS8311724-02 10 nmol

hsa-miR-4314 miRNA Agomir

Ask
View Details
hsa-miR-4314 miRNA Agomir
MBS8311724-03 20 nmol

hsa-miR-4314 miRNA Agomir

Ask
View Details