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Anti-Phospho-C3G (Y504) RAPGEF1 Antibody

Boster Bio Anti-Phospho-C3G (Y504) RAPGEF1 Antibody catalog # A06527Y504. Tested in ELISA, WB applications. This antibody reacts with Human.

Product Specifications

Synonyms

Rap guanine nucleotide exchange factor 1; CRK SH3-binding GNRP; Guanine nucleotide-releasing factor 2; Protein C3G; RAPGEF1; GRF2;

Gene Name

RAPGEF1

UniProt

Q13905

Host

Rabbit

Reactivity

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human RapGEF1 around the phosphorylation site of Tyr504. AA range:470-519

Clonality

Polyclonal

Tissue Specificity

Ubiquitously expressed in adult and fetus. Expression is high in adult skeletal muscle and placenta and in fetal brain and heart. Low levels of expression in adult and fetal liver.

Applications

WB, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Guanine nucleotide-releasing protein that binds to SH3 domain of CRK and GRB2/ASH. Transduces signals from CRK to activate RAS. Plays a role in the establishment of basal endothelial barrier function. Plays a role in nerve growth factor (NGF) -induced sustained activation of Rap1 and neurite outgrowth.

Molecular Weight

120548 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A06527Y504

Product MSDS

https://www.bosterbio.com/msds?sku=A06527Y504

Fragment

IgG

Other Gene Names

Rap guanine nucleotide exchange factor 1

Subcellular Location

Early endosome

Protein Name

Rap guanine nucleotide exchange factor 1

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