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Anti-SCIN Rabbit Monoclonal Antibody

Boster Bio Anti-SCIN Rabbit Monoclonal Antibody catalog # M07463. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Trophoblast glycoprotein;5T4 oncofetal antigen;5T4 oncofetal trophoblast glycoprotein;5T4 oncotrophoblast glycoprotein; M6P1; Wnt-activated inhibitory factor 1; WAIF1; TPBG;5T4

Gene Name

Trophoblast glycoprotein

UniProt

Q9Y6U3

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human SCIN

Clonality

Monoclonal

Clone

Clone: 27S73

Tissue Specificity

Expressed by all types of trophoblasts as early as 9 weeks of development. Specific for trophoblastic cells except for amniotic epithelium. In adult tissues, the expression is limited to a few epithelial cell types but is found on a variety of carcinoma.

Applications

WB, IHC

Field of Research

Cancer, Developmental Biology, Lineage Markers, Lineage Specification, Stem Cells, Tumor Immunology, Tumor-Associated Antigens

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

May function as an inhibitor of Wnt/beta-catenin signaling by inly interacting with LRP6 and blocking Wnt3a- dependent LRP6 internalization. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=M07463

Product MSDS

https://www.bosterbio.com/msds?sku=M07463

Fragment

IgG

Applications Notes

WB 1:500-1:2000<br>IHC 1:50-1:200

Other Gene Names

SCIN

Subcellular Location

Cell membrane ; Single-pass type I membrane protein .

Protein Name

T-cell surface glycoprotein CD3 zeta chain

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