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Anti-WRN Rabbit Monoclonal Antibody

Boster Bio Anti-WRN Rabbit Monoclonal Antibody catalog # M00873. Tested in WB application. This antibody reacts with Human.

Product Specifications

Synonyms

Multidrug resistance-associated protein 1; ATP-binding cassette sub-family C member 1; Leukotriene C (4) transporter; LTC4 transporter; ABCC1; MRP, MRP1

Gene Name

Multidrug resistance-associated protein 1

UniProt

Q14191

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human WRN

Clonality

Monoclonal

Clone

Clone: 24W80

Tissue Specificity

Lung, testis and peripheral blood mononuclear cells.

Applications

WB

Field of Research

ATPases, Cancer, Channels, Drug Metabolism, Metabolic Signaling Pathways, Metabolism, Pathways and Processes, Plasma Membrane, Signal Transduction

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o- glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs. Hydrolyzes ATP with low efficiency. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=M00873

Product MSDS

https://www.bosterbio.com/msds?sku=M00873

Fragment

IgG

Applications Notes

WB 1:500-1:2000

Other Gene Names

WRN

Subcellular Location

Cell membrane ; Multi-pass membrane protein .

Protein Name

Glycogen synthase kinase-3 beta (gsk3b)

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