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Anti-Cystatin A Rabbit Monoclonal Antibody

Boster Bio Anti-Cystatin A Rabbit Monoclonal Antibody catalog # M03914. Tested in WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Cell division cycle protein 27 homolog; Anaphase-promoting complex subunit 3; APC3; CDC27 homolog; CDC27Hs; H-NUC; CDC27; ANAPC3, D0S1430E, D17S978E

Gene Name

Cell division cycle protein 27 homolog

UniProt

P01040

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human Cystatin A

Clonality

Monoclonal

Clone

Clone: 24C70

Tissue Specificity

Abundantly expressed in brain, heart and pancreas, and at lower levels in kidney and placenta. Up-regulated in the lumbar spinal cord from patients with sporadic amyotrophic lateral sclerosis (ALS) compared with controls, with highest levels of expression in individuals with predominant lower motor neuron involvement. .

Applications

WB, Flow Cytometry

Field of Research

Cell Biology, Cell Cycle, Cell Division, Proteasome / Ubiquitin, Proteolysis/Ubiquitin, Spindle

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=M03914

Product MSDS

https://www.bosterbio.com/msds?sku=M03914

Fragment

IgG

Applications Notes

WB 1:500-1:2000<br>FC 1:50

Other Gene Names

CSTA

Subcellular Location

Nucleus.

Protein Name

T-cell surface glycoprotein CD3 zeta chain

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