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Anti-CAD Rabbit Monoclonal Antibody

Boster Bio Anti-CAD Rabbit Monoclonal Antibody catalog # M00463-1. Tested in WB, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human.

Product Specifications

Synonyms

Toll-like receptor 5; Toll/interleukin-1 receptor-like protein 3; TLR5; TIL3

Gene Name

Toll-like receptor 5

UniProt

P27708

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human CAD

Clonality

Monoclonal

Clone

Clone: 23C35

Tissue Specificity

Highly expressed in ovary and in peripheral blood leukocytes, especially in monocytes, less in CD11c+ immature dendritic cells. Also detected in prostate and testis.

Applications

WB, ICC, IF, IP, Flow Cytometry

Field of Research

Immunoglobulins, Immunology, Innate Immunity, Macrophage/Inflammation, Receptors, TLR Signaling

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Participates in the innate immune response to microbial agents. Mediates detection of bacterial flagellins. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=M00463-1

Product MSDS

https://www.bosterbio.com/msds?sku=M00463-1

Fragment

IgG

Applications Notes

WB 1:500-1:1000<br>ICC/IF 1:50-1:200<br>IP 1:30<br>FC 1:80

Other Gene Names

CAD

Subcellular Location

Membrane ; Single-pass type I membrane protein .

Protein Name

T-cell surface glycoprotein CD4

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