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Anti-PRKAR1A Rabbit Monoclonal Antibody

Boster Bio Anti-PRKAR1A Rabbit Monoclonal Antibody catalog # M00699-1. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Tumor protein p73; p53-like transcription factor; p53-related protein; TP73; P73

Gene Name

Tumor protein p73

UniProt

P10644

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human PRKAR1A

Clonality

Monoclonal

Clone

Clone: 20P51

Tissue Specificity

Expressed in striatal neurons of patients with Huntington disease (at protein level) . Brain, kidney, placenta, colon, heart, liver, spleen, skeletal muscle, prostate, thymus and pancreas. Highly expressed in fetal tissue. .

Applications

WB, IHC, ICC, IF

Field of Research

Apoptosis, Cell Biology, Intracellular, p53 Pathway

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=M00699-1

Product MSDS

https://www.bosterbio.com/msds?sku=M00699-1

Fragment

IgG

Applications Notes

WB 1:500-1:2000<br>IHC 1:50-1:200<br>ICC/IF 1:50-1:200

Other Gene Names

PRKAR1A

Subcellular Location

Nucleus . Cytoplasm. Accumulates in the nucleus in response to DNA damage.

Protein Name

T-cell surface glycoprotein CD4

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