Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-PICK1 Rabbit Monoclonal Antibody

Boster Bio Anti-PICK1 Rabbit Monoclonal Antibody catalog # M02457-1. Tested in WB, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Major prion protein; PrP; ASCR; PrP27-30; PrP33-35C; CD230; PRNP; ALTPRP, PRIP, PRP

Gene Name

Major prion protein

UniProt

Q9NRD5

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human PICK1

Clonality

Monoclonal

Clone

Clone: 19P66

Tissue Specificity

Ubiquitous.

Applications

WB, IP, Flow Cytometry

Field of Research

Hematopoietic Progenitors, Neurodegenerative Disease, Neurology Process, Neuroscience, Stem Cells, Surface Molecules

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro) . Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu (2+) or ZN (2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan sulfate side chains (By similarity) . .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=M02457-1

Product MSDS

https://www.bosterbio.com/msds?sku=M02457-1

Fragment

IgG

Applications Notes

WB 1:500-1:2000<br>IP 1:50<br>FC 1:50

Other Gene Names

PICK1

Subcellular Location

Cell membrane; Lipid-anchor, GPI-anchor. Golgi apparatus. Targeted to lipid rafts via association with the heparan sulfate chains of GPC1. Colocates, in the presence of CU (2+), to vesicles in para- and perinuclear regions, where both proteins undergo internalization. Heparin displaces PRNP from lipid rafts and promotes endocytosis.

Protein Name

T-cell surface glycoprotein CD3 zeta chain

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Phospho-CDK1/CDK2/CDK3 (T14) Antibody
A10953-50UG 50 µg

Phospho-CDK1/CDK2/CDK3 (T14) Antibody

Ask
View Details
Receptor-interacting serine/threonine-protein kinase 3
MBS2888973 Inquire

Receptor-interacting serine/threonine-protein kinase 3

Ask
View Details
Sphingomyelin ELISA Kit
ECP7944 96 Tests

Sphingomyelin ELISA Kit

Ask
View Details
FOXO4 (NM_005938) Human Tagged ORF Clone Lentiviral Particle
RC213185L4V 200 µL

FOXO4 (NM_005938) Human Tagged ORF Clone Lentiviral Particle

Ask
View Details
NSUN7 Antibody (C-term)
E45R30580G-4 50 ul

NSUN7 Antibody (C-term)

Ask
View Details
Dishevelled 2 (DVL2) Human shRNA Plasmid Kit (Locus ID 1856)
TG313337 1 Kit

Dishevelled 2 (DVL2) Human shRNA Plasmid Kit (Locus ID 1856)

Ask
View Details