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Anti-Cullin 2 Rabbit Monoclonal Antibody

Boster Bio Anti-Cullin 2 Rabbit Monoclonal Antibody catalog # M02986-1. Tested in WB, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Golgi membrane protein 1; Golgi membrane protein GP73; Golgi phosphoprotein 2; GOLM1; C9orf155, GOLPH2; PSEC0242, UNQ686/PRO1326

Gene Name

Golgi membrane protein 1

UniProt

Q13617

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human Cullin 2

Clonality

Monoclonal

Clone

Clone: 19C43

Tissue Specificity

Widely expressed. Highly expressed in colon, prostate, trachea and stomach. Expressed at lower level in testis, muscle, lymphoid tissues, white blood cells and spleen. Predominantly expressed by cells of the epithelial lineage. Expressed at low level in normal liver. Expression significantly increases in virus (HBV, HCV) infected liver. Expression does not increase in liver disease due to non-viral causes (alcohol-induced liver disease, autoimmune hepatitis) . Increased expression in hepatocytes appears to be a general feature of advanced liver disease. In liver tissue from patients with adult giant-cell hepatitis (GCH), it is strongly expressed in hepatocytes-derived syncytial giant cells. Constitutively expressed by biliary epithelial cells but not by hepatocytes. .

Applications

WB, ICC, IF, IP, Flow Cytometry

Field of Research

Cell Type Markers, G Protein Signaling, Hematopoietic Progenitors, Immunology, More Gpcr, Neuroscience, Neurotransmission, Receptors / Channels, Signal Transduction, Signaling Pathway, Stem Cells

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Unknown. Cellular response protein to viral infection.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=M02986-1

Product MSDS

https://www.bosterbio.com/msds?sku=M02986-1

Fragment

IgG

Applications Notes

WB 1:500-1:2000<br>ICC/IF 1:50-1:200<br>IP 1:50<br>FC 1:50

Other Gene Names

CUL2

Subcellular Location

Golgi apparatus, cis-Golgi network membrane ; Single-pass type II membrane protein . Early Golgi. Cycles via the cell surface and endosomes upon lumenal pH disruption.

Protein Name

T-cell surface glycoprotein CD3 zeta chain

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